The article presents a comprehensive analysis of the applicability and efficiency of basic renewable energy sources (RES) in modern buildings, including high-rise and unique structures. A comparative analysis of key technologies—solar (PV and thermal), wind, geothermal (heat pumps), and bioenergy—was conducted, highlighting their specific advantages as determined by efficiency indicators, COP, capacity factor (CUF), and temperature potential. The selection methodology is implemented as a sequence of iterative steps based on international statistical data (IRENA, IEA), modeling tools, and multi-criteria analysis principles. Key engineering requirements for the external and internal units of solar (photovoltaic and thermal), wind, geothermal systems, and bioenergy are identified. It is established that the selection and design of RES systems are determined by a triad of imperatives: achieving architectural harmony, maximizing energy efficiency, and ensuring safety and durability. A universal solution does not exist, and the efficiency of integration is determined by a combination of factors: climatic conditions, architectural and structural features of the building, and its energy profile. A typology of solutions for different building classes – from mass multi-story construction to skyscrapers – is proposed, with a detailed examination of wind and vibration loads, thermal deformations, and installation logistics. It is proven that for complex facilities, a hybrid approach is optimal, combining, in particular, geothermal heat pumps, building integrated photovoltaics (BIPV), and adapted small wind turbines. The article emphasizes the necessity of interdisciplinary design at the intersection of architecture, energy engineering, and mechanics to create efficient energy-active buildings. The transition from assessing RES potential in general to designing adaptive solutions for specific buildings is a necessary condition for creating energy efficient and carbon neutral buildings. The practical value of the work lies in providing designers and developers with a structured decision-making tool, which contributes to the creation of energy efficient, carbon neutral buildings and a sustainable urban environment.